Phosphodiesterase Inhibitors

Phenolic glycosides from Symplocos racemosa: natural inhibitors of phosphodiesterase I

Phytochemistry / Medicinal Plants / Magnetic Resonance Spectroscopy / Snake venoms / Biological Sciences / Animals / CHEMICAL SCIENCES / Phosphodiesterase Inhibitors / Snake Venom / Isolation / Structure Elucidation / Phenols / Angiosperms / Biological activity / Glycosides / Molecular Structure / Animals / CHEMICAL SCIENCES / Phosphodiesterase Inhibitors / Snake Venom / Isolation / Structure Elucidation / Phenols / Angiosperms / Biological activity / Glycosides / Molecular Structure

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Phenolic glycosides from Symplocos racemosa: natural inhibitors of phosphodiesterase I

Phytochemistry / Medicinal Plants / Magnetic Resonance Spectroscopy / Snake venoms / Biological Sciences / Animals / CHEMICAL SCIENCES / Phosphodiesterase Inhibitors / Snake Venom / Isolation / Structure Elucidation / Phenols / Angiosperms / Biological activity / Glycosides / Molecular Structure / Animals / CHEMICAL SCIENCES / Phosphodiesterase Inhibitors / Snake Venom / Isolation / Structure Elucidation / Phenols / Angiosperms / Biological activity / Glycosides / Molecular Structure

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Discovery of a new series of [1,2,4]triazolo[4,3-a]quinoxalines as dual phosphodiesterase 2/phosphodiesterase 10 (PDE2/PDE10) inhibitors

Organic Chemistry / Drug Discovery / Animals / Male / Phosphodiesterase Inhibitors / Rats / Wistar Rats / Molecular Structure / Rats / Wistar Rats / Molecular Structure

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Systematic review of Viagra RCTs

Treatment Outcome / Humans / Male / Phosphodiesterase Inhibitors / Public health systems and services research / Bias (Epidemiology) / Review Literature As Topic / Bias (Epidemiology) / Review Literature As Topic

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Anaphylaxis due to caffeine

Immunology / Coffee / Allergy / Humans / Caffeine / Anaphylaxis / Male / Immunoglobulin E / Phosphodiesterase Inhibitors / Adult / Anaphylaxis / Male / Immunoglobulin E / Phosphodiesterase Inhibitors / Adult

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Phenolic glycosides from Symplocos racemosa: natural inhibitors of phosphodiesterase I

Phytochemistry / Medicinal Plants / Magnetic Resonance Spectroscopy / Snake venoms / Biological Sciences / Animals / CHEMICAL SCIENCES / Phosphodiesterase Inhibitors / Snake Venom / Structure Elucidation / Phenols / Angiosperms / Glycosides / Animals / CHEMICAL SCIENCES / Phosphodiesterase Inhibitors / Snake Venom / Structure Elucidation / Phenols / Angiosperms / Glycosides

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Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors

Organic Chemistry / Schizophrenia / Structure / Modeling / Macromolecular X-Ray Crystallography / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines

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Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors

Organic Chemistry / Schizophrenia / Structure / Modeling / Macromolecular X-Ray Crystallography / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines / In Vitro / Permeability / Animals / Phosphodiesterase Inhibitors / Rats / Molecular Model / Bioorganic and medicinal Chemistry / Benzimidazoles / Protein Binding / Chemical Synthesis / Molecular Structure / Quinazolines

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Successful Use of Phosphodiesterase Type 5 Inhibitors to Control Symptomatic Esophageal Hypercontractility: A Case Report

Gastroenterology / Motility / Case Report / Humans / Smooth muscle / Digestive and Liver Diseases / Thorax / Male / Lower Esophageal Sphincter / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Adult / Imidazoles / Triazines / Chest Pain / Calcium Channel Blocker / Proton Pump Inhibitor / Digestive and Liver Diseases / Thorax / Male / Lower Esophageal Sphincter / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Adult / Imidazoles / Triazines / Chest Pain / Calcium Channel Blocker / Proton Pump Inhibitor

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A single amino acid residue controls Ca2+ signaling by an octopamine receptor from Drosophila melanogaster

Physiology / Calcium / Drosophila melanogaster / Humans / Mutation / Animals / Calcium Signaling / Threonine / Phosphorylation / Medical Physiology / Phosphodiesterase Inhibitors / Amino Acid Sequence / Octopamine / Fluorometry / Intracellular Space / Maleimides / Biochemistry and cell biology / Animals / Calcium Signaling / Threonine / Phosphorylation / Medical Physiology / Phosphodiesterase Inhibitors / Amino Acid Sequence / Octopamine / Fluorometry / Intracellular Space / Maleimides / Biochemistry and cell biology

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7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 Inhibitors: A Potential Treatment for Asthma

Organic Chemistry / Animals / Phosphodiesterase Inhibitors / Pyridines / Bioorganic and medicinal Chemistry / Structure activity Relationship / Furans / Structure activity Relationship / Furans

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Successful Use of Phosphodiesterase Type 5 Inhibitors to Control Symptomatic Esophageal Hypercontractility: A Case Report

Gastroenterology / Motility / Case Report / Humans / Smooth muscle / Digestive and Liver Diseases / Thorax / Male / Lower Esophageal Sphincter / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Adult / Imidazoles / Triazines / Chest Pain / Calcium Channel Blocker / Proton Pump Inhibitor / Digestive and Liver Diseases / Thorax / Male / Lower Esophageal Sphincter / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Adult / Imidazoles / Triazines / Chest Pain / Calcium Channel Blocker / Proton Pump Inhibitor

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CoNSEnsX: an ensemble view of protein structures and NMR-derived experimental data

Molecular Dynamics Simulation / Software / Ubiquitin / Humans / Protein structure / Proteins / Phosphodiesterase Inhibitors / Web Service / Protein Conformation / Experimental Data / Internet / Proteins / Phosphodiesterase Inhibitors / Web Service / Protein Conformation / Experimental Data / Internet

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Successful Use of Phosphodiesterase Type 5 Inhibitors to Control Symptomatic Esophageal Hypercontractility: A Case Report

Gastroenterology / Motility / Case Report / Humans / Smooth muscle / Digestive and Liver Diseases / Thorax / Male / Lower Esophageal Sphincter / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Adult / Imidazoles / Triazines / Chest Pain / Calcium Channel Blocker / Proton Pump Inhibitor / Digestive and Liver Diseases / Thorax / Male / Lower Esophageal Sphincter / Enzyme / Clinical Sciences / Phosphodiesterase Inhibitors / Adult / Imidazoles / Triazines / Chest Pain / Calcium Channel Blocker / Proton Pump Inhibitor

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A New Locus for Autosomal Recessive Retinitis Pigmentosa (RP19) Maps to 1p13–1p21

Information Systems / Genetics / Genomics / Polymorphism / Humans / Retinitis pigmentosa / Female / Male / Linkage / Gene / Pedigree / Genetic linkage analysis / Phosphodiesterase Inhibitors / Aged / Gen / Genetic Mapping / Linkage Analysis / Molecular Sequence Data / Retinitis pigmentosa / Female / Male / Linkage / Gene / Pedigree / Genetic linkage analysis / Phosphodiesterase Inhibitors / Aged / Gen / Genetic Mapping / Linkage Analysis / Molecular Sequence Data

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A new locus for autosomal recessive retinitis pigmentosa (RP19) maps to 1p13-1p21

Information Systems / Genetics / Genomics / Polymorphism / Humans / Retinitis pigmentosa / Female / Male / Linkage / Gene / Pedigree / Genetic linkage analysis / Phosphodiesterase Inhibitors / Aged / Gen / Genetic Mapping / Linkage Analysis / Molecular Sequence Data / Retinitis pigmentosa / Female / Male / Linkage / Gene / Pedigree / Genetic linkage analysis / Phosphodiesterase Inhibitors / Aged / Gen / Genetic Mapping / Linkage Analysis / Molecular Sequence Data

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